TRIUMPH-1: obesity and overweight TRIUMPH-1 (NCT05929066) is the main weight management trial
Sibutramine Reason for Ban: Marketed as a weight-loss drug, Sibutramine was banned after clinical trials and post-market data revealed a significant increase in the risk of serious cardiovascular events, including heart attack and stroke
Lastly, a study has shown the involvement of glial cells and TNF- in the degeneration of respiratory nuclei and breathing dysfunction in mouse model of PD, underscoring the importance of neuroinflammation (Cabral et al., 2024
Like other GLP-1 drugs, Foundayo can cause side effects such as nausea, constipation, diarrhea, vomiting, abdominal pain, and headache, according to the FDA
Some patients may benefit from over-the-counter antacids, though any additional medications should be discussed with a pharmacist or GP to ensure compatibility with existing treatments