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A recent FDA 503A update in the U.S

Upon consumption, Cbl is usually bound to proteins and must be released from its protein-bound state through the action of stomach acid

[oai_citation:6PubMed]( [oai_citation:7PMC]( 5) Gastroprotective/cytoprotective actions in rodent models Multiple rat studies describe protection/healing in NSAID-induced and other gastric ulcer paradigms, consistent with mucosal cytoprotection concepts

Being a prescription-only treatment already primes it for safety since the prescribing physician will consider your medical history and may subject you to biomarker testing before writing you the script

Patients who take it often feel like moving around more and tend to burn more calories through increased movement