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Over time, long-term high serum uric acid (SUA) may cause many complications

Journal of Clinical Endocrinology & Metabolism, 92 (2), 549555

Mechanistically, T3 suppresses Cyp8b1 expression, resulting in increased the levels of Farnesoid X receptor (FXR)-antagonistic bile acids, thereby potentiating GLP-1 production and insulin secretion by repressing intestinal FXR signalling