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This article reviews current evidence, potential mechanisms, and practical guidance for patients and healthcare providers

Robert Ashley, MD, is an internist and assistant professor of medicine at the University of California, Los Angeles

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Wegovy, for example, comes in a multi-dose pen in Europe but only as a single-use pen in the United States

The primary endpoints are retatrutide's own AUC from time zero to infinity and its maximum observed concentration, sampled from predose out to 31 days