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After the shortage ended and enforcement discretion lapsed in early 2025, compounded tirzepatide is allowed through a 503A pharmacy only for a documented individualized clinical need an approved product cannot meet
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Contact your GP or NHS 111 if diarrhoea persists beyond 7 days or if you're passing more than 6 loose stools daily
Feeling cold is not listed as an official adverse effect in the Summary of Product Characteristics (SmPC) approved by the Medicines and Healthcare products Regulatory Agency (MHRA), though some patients report increased cold sensitivity during treatment
Molecules (Basel, Switzerland), 27 (13), 4315
Each of these GLP-1 medications provide important safety information on their websites including possible side effects from taking the drug
