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FDA Assessment FDAs 2026 briefing described major characterisation, effectiveness and safety limitations and proposed against inclusion on the 503A Bulks List
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545 NLRP6 also regulates the secretion of IL-18 and antimicrobial peptides in enterocytes, 546 as well as mucin production in goblet cells, 547 which contributes to its ability to prevent the invasion of pathobionts that initiate colitis-associated colorectal cancer 548 (Fig
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