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April 14, 2022
A transient peptide can produce a pulse of activity instead of a sustained alteration
Wang Q, Yang S, Wang K, Sun SY
This has called for new emerging strategies for improved bioavailability that include chemical modifications to stabilize the peptide, use of enzyme inhibitors, linkage to absorption enhancers, and packaging peptides using nanoparticles
6 It also complicates attribution: in a person taking both drugs, an observed gastric-emptying delay cannot be cleanly credited to cagrilintide
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