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In vitro glutathione deficiency alters vitamin D metabolism genes and VDR in mouse hepatocytes To rule out the non-specific effect of HFD conditions and other confounding variables in animals, we carried out in vitro experiments to determine the direct impact of glutathione deficiency status on VD metabolism genes in hepatocytes

-Tocopheryl esters (e.g., -tocopheryl acetate) from supplements or food fortificants must be hydrolyzed by pancreatic esterases to release -tocopherol for incorporation into micelles

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They are not a substitute for a healthy lifestyle