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Foundational reference: Hadley & Hruby, Discovery and development of novel melanogenic drugs (PMID 9760697)
Biochemistry 38(42):1378713794 Dekker LV, Parker PJ (1997) Regulated binding of the protein kinase C substrate GAP-43 to the V0/C2 region of protein kinase C-delta
The phase 2a liver-specific trial showed: 1 mg dose: 42.9% reduction in liver fat 4 mg dose: 57.0% reduction in liver fat 8 mg dose: 81.4% reduction in liver fat 12 mg dose: 82.4% reduction in liver fat An 82% reduction in liver fat is extraordinary
Sources of protein like chicken, fish, eggs, tofu, and legumes help support muscle mass and repair muscle tissue because they increase the amino acid levels in people
However, numerous patients have reported benefit while others have reported no benefit
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