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[2] Research indicates that ALA may improve symptoms of diabetic neuropathy: for example, clinical trials and meta-analyses have shown that intravenous ALA (typically 600 mg per day for 3 weeks) may significantly reduce neuropathic pain, paresthesia, and numbness in diabetic patients

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Chronic wounds are often associated with a patients inability to sufficiently (correctly) heal and clear the source or cause of the attrition, such as in chronic infections or metabolic disorders