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SLC22A5 mutations impair OCTN2 function, causing primary carnitine deficiency (PCD) (1517), an autosomal recessive disorder characterized by skeletal myopathy, progressive cardiomyopathy, hypoglycemia, and hyperammonemia
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MCs and basophils are considered the predominant histamine sources
A thin layer of 1% hydrocortisone cream applied to the injection site reduces both itching and inflammation
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