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GLP-1 receptor (GLP-1R) is widely distributed in the central nervous system, mainly in neurons (Vrang and Larsen, 2010), with high expression in glutamatergic neurons of the area postrema (AP) and nucleus of the solitary tract (NTS) (Ludwig et al., 2021a

The clinicians determine eligibility on their own and can refuse treatment when not clinically appropriate

These can include improved mood, enhanced mental clarity, and better sleep patterns

When the last fact (the outcome of interests or other medical encounters) in the patients record is in the time window for analysis, the patient was censored on the day after the last fact in their record

This gives the underlying tissue time to heal and prevents the buildup of hardened areas that make injections more difficult