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Although metformin is extremely efficient, its absorbtion is poor and variable
It may influence the gut-brain axis, HPA (hypothalamic-pituitary-adrenal) axis, and broader hormonal loops involved in energy balance and stress response
That means it converts to vitamin A in the body only as needed
Adjunctive topical agents may be applied during treatment depending on clinical judgement
At the conference, a date was also set for the Rule 702 hearing
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