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(1997b)
We hypothesize that the influence of SFN on the gut microbiota is at least partly related to the effects on their habitat, i.e., the gut such as (i) alleviation of oxidative stress and inflammation in the intestine, (ii) increase of the expression of tight junction proteins, preventing excessive intestinal permeability and invasion of luminal bacteria, and (iii) promotion of gut detoxification capability via increase of activity of phase II detoxification enzymes such as GSTs
A previous meta-analysis of NAC use in COPD found that it reduced the occurrence of exacerbations by roughly half over the treatment period, an effect somewhat attenuated by simultaneous steroid use, but not active smoking.Men with idiopathic infertility given 600mg per day had improvement in several semen parameters as well as plasma antioxidant status
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