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Cancer Epidemiol Biomarkers Prev 2004;13(3):340345
In PTSD mice models, trauma exposure increased tyrosine hydroxylase expression (the rate-limiting enzyme in catecholamine biosynthesis), elevating stress hormones epinephrine and norepinephrine in serum and colon, which upregulated claudin-2 expression, confirming gut barrier dysfunction (Yadav et al., 2023)
PubMed , Monatshefte Fr Chemie / Chemical Monthly , vol
Erden-Inal M, Sunal E, Kanbak G: Age-related changes in the glutathione redox system
While LAC is an exciting potential biomarker for depression, McEwen stressed that more research is necessary
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