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Mechanisms Of Action Simple: Methylation is a cycle: folate donates a methyl group to homocysteine (with B12), homocysteine becomes methionine, methionine becomes SAM-e, SAM-e donates methyl groups to 200+ reactions, and the cycle restarts
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doi: 10.1006/exer.1997.0353 44 TsaiCCKaoSCChengCYKauHCHsuWMLeeCFet al
References: Almohanna et al
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