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Semaglutide is a glucagon-like peptide-1 (GLP-1) receptor agonist, while metformin belongs to a class of medications called biguanides

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Overview of the Phase 2 NEJM Trial Design and Participants Weight Loss Results at 48 Weeks: Key Percentage Findings Safety Profile and Side Effects Reported in the Trial How These Results Compare to Other Weight Loss Medicines What the Findings Mean for Future Treatment in the UK Scientific References Frequently Asked Questions What Is Retatrutide and How Does It Work

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Clin Pharmacokinet 57 , 15711580 (2018)

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