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Diabetologia 55(9):23432347
Preclinical and translational studies have examined cagrilintide in the context of body-weight reduction driven largely by reduced energy intake and altered metabolic signaling
Nonetheless, the pharmacological activation of the GLP-1R is clinically beneficial (179), offering an improved glycaemic control with lower cardiovascular morbidity and without the risk of hypoglycaemia associated with some current anti diabetic drugs (173)
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