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Herein, we discuss some critical examples of representative synthetic compounds

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Angew Chem Int Ed 50(33):76457649

Clear indicators of degradation Cloudiness or haziness

Langman CB, Greenbaum LA, Sarwal M, Grimm P, Niaudet P, Deschenes G, Cornelissen E, Morin D, Cochat P, Matossian D, Gaillard S, Bagger MJ, Rioux P (2012) A randomized controlled crossover trial with delayed-release cysteamine bitartrate in nephropathic cystinosis: effectiveness on white blood cell cystine levels and comparison of safety