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Holst reflects on the multi-decade journey from the discovery of GLP-1 in 1986 to its current use as a weekly injectable drug
Section 503A, in turn, allows for patient-specific compounding performed by (1) a licensed pharmacist in a state-licensed pharmacy or federal facility, or (2) a licensed physician for example, for patients who are allergic to certain inactive ingredients, need a liquid formulation rather than a pill, or need a lower strength than what is commercially available The Rise and Fall of GLP-1 Compounding As we detailed here, compounding pharmacies entered the GLP-1 market in 2022 when demand for semaglutide and tirzepatide outstripped supply and both drugs hit the FDA Drug Shortage List, resulting in the emergence of a multibillion-dollar sub-industry
Always check for FDA approval before switching from a brand-name drug to a generic
MESNA is a chemoprotective agent used to prevent hemorrhagic cystitis caused by ifosfamide
A 2024 review indicated that small pilot studies suggest GLP-1s can reduce some eating disorders, but researchers said more rigorously collected data is needed
