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This improvement was associated with a modulation of the endoplasmic reticulum (ER) stress response, reflected in suppressed levels of C/EBP homologous transcription factor protein (CHOP), a proapoptotic factor, and increased expression of glucose regulatory protein 78, a chaperone protecting against ER stress

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Dietary Supplementation with Glycine Enhances Intestinal Mucosal Integrity and Ameliorates Inflammation in C57BL/6J Mice with High-Fat Diet-Induced Obesity Coppola L., et al (1992)