Proton pump inhibitors (omeprazole, esomeprazole)
NDH at 42-47 mmol/mol or 6.0-6.4%), fasting plasma glucose (diabetes 7.0 mmol/L), lipid profiles, and thyroid function tests as clinically indicated
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It has been approved as a second line treatment option for better glycaemic control in type 2 diabetes and currently under scrutiny for anti-obesity purpose
It was found that administration of di(2-ethylhexyl)phthalate (DEHP), a peroxisomal proliferator, to Wistar rats led to an increase in the expression of CROT by a factor of 14.1