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Research has shown increased phosphorylation of extracellular signal-regulated kinases (ERK) 1 and 2, along with their downstream targets, including c-Fos, c-Jun, and Egr-1, which are molecules involved in cell growth, migration, and angiogenesis
Lee NC, Tang NL, Chien YH, Chen CA, Lin SJ, Chiu PC, et al
One group received only the medications, another received the medications plus ALC, and the third group received placebo
In a rat Achilles tendon injury model, Western blot and immunobiological staining results showed more IGF-1 in the injured tendon following local administration of IGFBP-4
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