What Experts Say: Medical professionals emphasize that tirzepatides benefitslike significant weight loss and improved metabolic healthoften outweigh the risks for eligible patients
In addition to the weight loss effect, it has been shown to improve various risk factors, such as blood pressure, dyslipidemia, and blood glucose levels, which are closely related to obesity
In one clinical trial, people who stopped tirzepatide (Zepbound) regained about 14% of their body weight over the following year, while those who continued treatment lost additional weight
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"All these new formulations are coming out," said Brian Roe, an Ohio State professor of food, agricultural and environmental sciences who led the GLP-1 study