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Autistic disorder in 2 children with mitochondrial disorders
Its molecular structure is associated with receptor-mediated activation patterns linked to endogenous hormone regulation pathways and downstream biomarker responses
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The distinct mode of CTR and AMYR engagement by Cagri revealed in the current study, together with the correlated distinctions in functional responses at individual receptors, is likely to be important in the differentiated, high efficacy, of Cagri as a first-in-class obesity drug in both preclinical animal models and in treatment of obese patients in clinical trials 2,3,4
