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Biomarkers we test for include CMP, Fasting Lipid, TSH with Reflex to T4, Hemoglobin A1C, and Insulin
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Sarkhosh-Inanlou R, Molaparast M, Mohammadzadeh A, Shafiei-Irannejad V
Other safety signals observed in preclinical and early clinical studies include changes in heart rate and as with other glucagon receptor agonists potential effects on hepatic glucose metabolism
The approval was granted based on demonstrated improvements in MASH and fibrosis, and a confirmatory study is currently underway
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