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After treatment with deferoxamine (DFO, an iron chelator), the abnormal iron content and sperm defects can be reversed [69, 70]

Clin Chem 39 : 17641779

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Type 2 Diabetes (Oral Therapy)# Recommendation : Orforglipron Reason : ACHIEVE-3 directly demonstrated orforglipron 36 mg superiority over oral semaglutide 14 mg for HbA1c reduction (2.2% vs 1.4%) and weight loss (9.2% vs 5.3%) in type 2 diabetes

That assumption holds in a stable-weight adult, but not when people are losing weight