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AAPS PharmSciTech (2013) 14:108397
The ratio of eumelanin to pheomelanin is genetically determined by a number of factors including the degree of base-line functional activity of the enzymes and proteins driving the mixed melanogenesis, by the melanocortin 1 receptor (MC1R) genetic polymorphism, and by the amount of the tyrosine in the melanosome [6]
doi: 10.1136/bmj.b277
Cardiovascular exercise provides additional metabolic and cardiovascular benefits, but should complement rather than replace resistance training
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