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Kuritzky L, Umpierrez G, Ekoe JM, Mancillas-Adame L, Lando LF
[30] [31] [32] The first and rate-limiting step in the AAA pathway is the condensation reaction between acetyl-CoA and ketoglutarate catalysed by homocitrate-synthase (HCS) (E.C 2.3.3.14) to give the intermediate homocitrylCoA, which is hydrolysed by the same enzyme to produce homocitrate
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Childhood constipation: evaluation and management
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