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27 At the 1-, 2-, and 3-year timepoints, they found that the GLP-1 RA cohort had a significantly lower risk of all three outcomes compared with metformin users

GLP-1 works beautifullystimulating insulin, suppressing glucagon, and slowing gastric emptyingbut it has a fatal flaw: It is destroyed by the enzyme DPP-4 within minutes of entering the bloodstream

DMH, dorsomedial hypothalamus

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Effects of delta-sleep-inducing peptide on 24-hour sleep-wake behaviour in severe chronic insomnia