GLP-1 suppresses glucagon secretion in human pancreatic alpha-cells by inhibition of P/Q-type Ca(2+) channels
also activates a second gut hormone receptor, GIP (glucose-dependent insulinotropic polypeptide) Plot twist: GLP-1 receptors are scattered throughout the body - including on immune cells and in the ovaries Here's where it gets interesting
The bottom line re GLP-1s GLP-1 is a hormone that helps control blood sugar and appetite and is now being studied for its potential to slow aging and extend healthy years of life
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The mitochondria, the cells energy-producing powerhouse, are also a significant source of free radical production, even in healthy individuals