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Dial 911 (or a local emergency number)

As far back as the 1970s, there were case reports in the literature of B12 deficiency associated with metformin use, with several observational studies reporting the same, but very little in the way of high-quality, well-powered, prospective studies

Higher doses (1,5005,000 IU multiple times weekly) are used to restore spermatogenesis and endogenous testosterone production in cases of hypogonadotropic hypogonadism or postanabolic steroid recovery [5] [6]

Rarely reported symptoms associated with excessive B12 intake may include: Skin reactions : Acne-like eruptions or rosacea-type dermatitis have been occasionally reported, particularly with high-dose intramuscular injections Gastrointestinal disturbance : Mild nausea, diarrhoea, or abdominal discomfort, though these are uncommon Headache : Infrequent reports of headaches following parenteral B12 administration Hypersensitivity reactions : In very rare cases, allergic reactions to injectable B12 preparations have been documented It is crucial to note that there is no established link between standard B12 supplementation and serious adverse effects

If you buy your B12 from us, each vial comes with an expiration date of just under a year, since an expiration date is required to be on all vitamins