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Clinical trials show that approximately 10-15% of patients may be considered "non-responders" who lose less than 5% of body weight after 3-4 months on a maintenance dose

Exposure to oral semaglutide was also slightly increased when administered with omeprazole compared with when administered alone (AUC 024 h,Day10 ), but this difference was not statistically significant (estimated treatment ratio: 1.13

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As with any medication, potential side effects, drug interactions, and contraindications must be reviewed