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Although preclinical data show promise (Loftis et al., 2013), their clinical applicability remains unclear owing to challenges, such as immune response variability and limited human trials

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Figure 6: The common cultivated button mushroom is low in ergothioneine compared to many other wild and cultivated mushrooms

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These likely result from both peptides effects on angiogenesis, endothelial protection, and inflammation reduction

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Eur J Clin Pharmacol 27:5759 Arana A, Morton NS, Hansen TG (2001) Treatment with paracetamol in infants

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Cells 11:682

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