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In a study examining the effects of LC supplementation on plasma and skeletal muscle carnitine concentrations and physical performance in 16 vegetarian and 8 omnivorous male volunteers, the plasma carnitine levels in vegetarians were 10% lower at baseline than those of omnivores
Tirzepatide (15 mg weekly) drives 15.7% weight loss over 72 weeks in patients with obesity and T2D (45) and 22.5% weight loss in patients with obesity alone (46)
You might take berberine with main meals (to reduce gastrointestinal effects and support its glucose-modulating actions) and L-carnitine either with meals or separately, depending on your routine and tolerance
Genazzani AD, Despini G, Czyzyk A, Podfigurna A, Simoncini T, Meczekalski B
Treatment starts at a low dose and is gradually increased to improve tolerability
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