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The supernatant was collected and mixed in a 1:1 ratio with methanol
The realistic expectation is hydration improvement visible within 48 hours, surface texture refinement by week 4, fine-line softening from week 8, and cumulative collagen-driven firmness from month 3 onward, sustained through bi-weekly sessions over 4 to 6 months
Neuro Endocrinol Lett 2003;24:32933 Epigenetic Variations in Chromatin Caused by the Combination of Bioregulators with Heavy Metals During Aging | International Journal of Peptide Research and Therapeutics n.d
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