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Hess, D

Endothelial senescence (2025, PMC) Reported FOXO4-DRI clearing senescent endothelial cells via a p53/BCL-2/caspase-3 pathway in animal and cell models

Here, we evaluated the effects of RESV through the modulation of TRPV4 on Ca 2+ influx, ROS-mediated pain, apoptosis, and oxidative damage in the mouse dorsal root ganglion (DRGs)

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In research models, inhibiting NNMT has been associated with preserved SAM and NAD availability, which is the mechanistic basis for studies into cellular energy and substrate handling