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Cagrilintide's C20 fatty-diacid modification extends half-life to ~7 days, making it viable for once-weekly dosing alongside semaglutide or tirzepatide
These gastrointestinal symptoms are typically most pronounced during dose escalation and often improve with continued use
There were no issues with clinical or efficacy data and the FDA is not seeking additional trials or data to support pz-cels application, according to Abeonas announcement
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As these therapies move into broader use, addressing these real-world complexities will be essential to realizing their full potential
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