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Therefore, it is known that, in some cases, where the liver is unable to perform effectively (whether it be from clinical disease, medications, alcohol abuse, protein digestion issues such as leaky gut, lack of stomach acid (PPIs), NFLS or gluten intolerance), the build-up of toxins and the use of amino acids for detoxification could suffer, as the availability of amino acids for its functionality is challenged
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Riboflavin as a Determinant of the Kynurenine Pathway Kynurenine pathway is the main tryptophan catabolism pathway, with neuroactive metabolites known as kynurenines
It is not clear how DHA affects brain function, but changes in DHA content of neuronal cell membranes could alter the function of ion channels or membrane-associated receptors, as well as the availability of neurotransmitters (94)