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Melanotan I (afamelanotide, brand Scenesse) selectively targets MC1R for tanning with fewer side effects and is EU-approved for erythropoietic protoporphyria
& Nyhus, L
Early research has suggested that GLP-1s may also reduce cravings for other addictive substances, like cocaine
In addition, semaglutide treatment reduced C-reactive protein levels, a marker of systemic inflammation that is known to be elevated in patients with obesity 25,26
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