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The diuretic and natriuretic effects of GLP-1 are mediated through downregulation of sodiumhydrogen exchanger 3 (NHE3) activity in the renal proximal tubule that consequently affects renal hemodynamics [112]
This can enhance digestion and reduce constipation symptoms
While ER imaging (ultrasound, CT, or HIDA scans) can help document gallbladder issues, operative and pathology reports are often stronger evidence in linking the injury to GLP1 exposure
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High oxidative stress levels have been linked to cardiovascular disease, cancer, inflammatory diseases, cataracts, and neurodegenerative disorders (Zakeri et al., 2021)
