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Why the Exact Half-Life Is Unclear Several major gaps still exist in the research: This uncertainty is important because many websites present exact numbers as facts when the evidence does not fully support those conclusions

43 Although causative effect has not been established, DPP-4 inhibitor therapy should be discontinued immediately if a patient presents with signs of pancreatitis, such as severe abdominal pain, nausea, vomiting, and weight loss

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Others found that their symptoms were more pronounced with the 1mg dose than with the 0.5mg dose