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So those approved titration schedules are the evidence-based doses, he says

Other good sources include salmon with 3 mcg for 3 ounces and tuna with 2.5 mcg for 3 ounces [1]

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Periconception safety within a precautionary gray zone: an absence of a stable teratogenic pattern is not synonymous with proven safety. In the absence of robust human exposure-outcome evidence, periconception management must adhere to a defensive principle: continuous effective contraception combined with adherence to drug-specific discontinuation and washout protocols remains the mandatory safety boundary