While they come from post-hoc analyses of an existing trial, the results build a picture of efficacy for oral semaglutide as Novo Nordisk prepares to compete in what is expected to be the next big frontier in obesity therapy the shift from injectable to daily oral therapies
Hkfelt, T., Johansson, O., Fuxe, K., Goldstein, M
Changes from baseline in cardiovascular, metabolic, and inflammatory biomarkers among GLP-1 drug users were as follows: Triglycerides: -16.4 mg/dL LDL cholesterol: -7.3 mg/dL HbA1c: -0.3 percentage points CRP: -0.6 mg/dL ESR: -3.0 mm/hr These were all numerically greater than corresponding changes for non-users, but often the differences didn't reach statistical significance
Thanks to its antioxidant properties, it has been found to have several benefits, particularly for skin and immune health
Christina Cauliffe, Head Athletic Trainer, Upper and Middle School Health Teacher, and Health and Wellness Department Chair, shared her own thoughts on Celcius