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When glutathione is abundant, detox runs smoothly
We found that at physiological pH, the rate-limiting step is the formation of a hydroxide ion
Mounting evidence has demonstrated that ferroptosis could be initiated and implemented by assorted intracellular metabolic processes, including amino acid, lipid peroxidation, and iron metabolism (Figure 1)
Conclusion The difference between glutathione and reduced glutathione is not significant because glutathione is an antioxidant, and reduced glutathione is one of its forms
J-RW: Writing original draft
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