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Mechanistic experiments using the PI3K inhibitor wortmannin demonstrated that PI3K/AKT signaling is required for the anti-inflammatory and anti-apoptotic effects, identifying the brain AngIV/PI3K/AKT axis as the proximate mechanism in this model
Oral supplements and oral vitamin B12 are also effective methods of supplementation
The peptide appears to reduce mucosal inflammation, accelerate intestinal healing, and restore intestinal barrier function
- [L-Cysteine]: An amino acid containing sulfur (S), L-cysteine is a precursor to glutathione synthesis in cells and is essential for the synthesis of glutathione
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