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Plan for at least 20 weeks of titration plus 12-28 weeks of maintenance at your target dose
to reduce the risk of major cardiovascular events such as heart attack, stroke or death in adults with type 2 diabetes with known heart disease
This process helps individuals adhere to a reduced-calorie diet and avoid overeating, thereby promoting weight loss
Both medications are used off-label for PCOS
Furthermore, the demonstration of cardiovascular benefits across a broad range of adiposity levels, coupled with independence from weight loss magnitude, suggests that semaglutide and perhaps other GLP-1 receptor agonists should be reconceptualized as cardiovascular disease-modifying agents rather than solely medications for glycemic control or weight loss
