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REVIEW OF THE LITERATURE Potential therapeutic mechanisms of N-acetylcysteine NAC possesses multiple beneficial pharmacological properties, e.g., anti-inflammatory, antioxidant, minimises cytokine action, modulation release of dopamine, reversing of mitochondrial malfunction, diminishes apoptosis and ferroptosis, improved neurogenesis and boosted glutamate release

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These improvements can greatly enhance the quality of life and further decrease health-related expenditures

Moreover, OsGSTL1 and OsGSTL2 are both constitutively expressed and involved in xenobiotic and oxidative stress tolerance in rice, whereas OsGSTL2 is also specifically up-regulated in roots after herbicide (chlorsulfuron and glyphosate) and hormone treatments (salicylic acid and naphthalene acetic acid) (Hu et al., 2009, 2011a,b)

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