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In general, methylation of CpG islands in promoter regions inhibits transcription
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In a randomized placebo-controlled trial in 36 subjects with mild-to-moderate asthma, 200 mg per day of a one-to-one combination of Aegle marmelos extract (standardized to contain 0.3% imperatorin) plus Boswellia serrata extract (standardized to contain 15% AKBA) reduced asthma symptoms after 14 days compared with placebo
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