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Incretin hormones are made in your small intestine and work in the following ways: Trigger the release of insulin from your pancreas to lower the amount of sugar in your blood Prevent extra sugar from entering your blood as a hormone called glucagon Slow food digestion and food emptying from your stomach Affect the areas of your brain that make you feel full If you have type 2 diabetes: Incretin hormones in the body dont work as well in patients with type 2 diabetes
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As the total number of studies investigating GLP-1 + cell numbers and function in the context of intestinal inflammation is limited and results are conflicting (26, 27, 3234), we quantified numbers of GLP-1 expressing cells in 4 different mouse models of ileal and colonic inflammation ( Tnf ARE mice (ileitis), IL-10 -/- mice and adoptive T cell-transfer model (colitis) as well as Citrobacter rodentium -infection (colitis))
